More than 200,000 men will be diagnosed with prostate cancer in the
United States this year. But despite the number of treatment options,
many men will undergo radical surgery without considering other, less
invasive procedures that might be just as effective.
One reason men don't learn of other options is that prostate cancer
patients typically are referred to urological surgeons. Many of the
newer treatment possibilities are performed by other physicians, such
as radiation oncologists.
Millions of men of the baby boomer generation, born between 1946 and
1964, will start turning 60 in the next few years. Many of these men
will be diagnosed with prostate cancer, and it's likely that their
biggest fear about prostate cancer treatment is whether it will render
them impotent.
However, according to a recent 10-year study released by Loma Linda
University Medical Center in Southern California, proton therapy offers
men a considerable advantage over unwanted side effects that often
occur with radical surgery or other forms of radiation treatment.
Proton therapy is the most precise, and the most advanced form of
radiation treatment. The physical properties of protons, compared to
standard X-ray radiation, allow for the ionization of the tumor site,
while leaving surrounding healthy tissue and organs intact.
Standard X-ray radiation therapy often radiates healthy cells and
tissue in its path and surrounding the tumor. Unwanted side effects are
much harder to control with standard radiation. Proton therapy offers
superior control along with the potential for higher doses to improve
long-term results.
Proton therapy has extended its reach in the number of clinical centers
that offer the therapy, in the number and types of cancers being
treated with it, and in the number of patients receiving the treatment.
Besides Loma Linda, the Midwest Proton Radiotherapy Institute at
Indiana University and the Northeast Proton Center at Boston's
Massachusetts General Hospital are treating patients. Centers in
development include: M.D. Anderson Cancer Center, Houston; Shands
Jacksonville, Florida Medical Center; and the University of
Pennsylvania, Philadelphia.
The Loma Linda study looked at 1,255 men treated for prostate cancer
during the 1990s. It was published in the International Journal of
Radiation and Oncology on June 1, 2004. Loma Linda analyzed results of
proton radiation therapy for localized cancer, with emphasis on
biochemical freedom and relapse.
The study concluded that proton therapy at the reported dose levels
yielded disease-free survival rates comparable with other forms of
local therapy, and with minimal to no side effects or morbidity.
Proton therapy especially compares well to radical surgery without
unwanted long-term problems. Long-term survival outcomes were
comparable to those reported for other modalities intended for cure.
The key treatment advantage with protons is the lack of commonly known
side effects.
Treatment time with proton therapy has declined in the past 10 years
with some treatments for patients with cancer requiring as little as
one treatment. As technology continues to improve, specialists expect
proton therapy to be used to treat more advanced stages of various
types of cancer in the future.
